Women with ovaries but no uterus may be able to use a gestational carrier. This may also be an option for women who shouldn't become pregnant because of a serious health problem. In this case, a woman uses her own egg. It is fertilized by the man's sperm and the embryo is placed inside the carrier's uterus. The carrier will not be related to the baby and gives him or her to the parents at birth.

If a Rh-negative woman conceives a Rh-positive baby, she is exposed to Rh protein, which is a blood group protein present on the surface of your cells. The first baby is delivered normally. For the next Rh positive baby, the mother has antibodies which destroy the baby at an early stage. However, this is debatable whether it is an infertility issue any longer. It is secondary infertility only when the woman is unaware of it. Otherwise, the female is fertile.

Premature ovarian insufficiencyexternal icon (POI). POI, sometimes referred to as premature menopause, occurs when a woman’s ovaries fail before she is 40 years of age. Although certain exposures, such as chemotherapy or pelvic radiation therapy, and certain medical conditions may cause POI, the cause is often unexplained. About 5% to10% of women with POI conceive naturally and have a normal pregnancy.


Twelve percent of all infertility cases are a result of a woman either being underweight or overweight. Fat cells produce estrogen,[13] in addition to the primary sex organs. Too much body fat causes production of too much estrogen and the body begins to react as if it is on birth control, limiting the odds of getting pregnant.[9] Too little body fat causes insufficient production of estrogen and disruption of the menstrual cycle.[9] Both under and overweight women have irregular cycles in which ovulation does not occur or is inadequate.[9] Proper nutrition in early life is also a major factor for later fertility.[14]
Gonadotropins. Instead of stimulating the pituitary gland to release more hormones, these injected treatments stimulate the ovary directly to produce multiple eggs. Gonadotropin medications include human menopausal gonadotropin or hMG (Menopur) and FSH (Gonal-F, Follistim AQ, Bravelle). Another gonadotropin, human chorionic gonadotropin (Ovidrel, Pregnyl), is used to mature the eggs and trigger their release at the time of ovulation. Concerns exist that there's a higher risk of conceiving multiples and having a premature delivery with gonadotropin use.

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In addition to keeping stress levels low, getting adequate sleep is vitally important at improving fertility. The average woman (30 to 60 years old) gets only six hours and 41 minutes of sleep during the work week, according to the National Sleep Foundation. Research has shown that not clocking enough hours of sleep each night can negatively impact your ability to conceive.
Depending on a woman’s symptoms, the uterusexternal icon may be evaluated by transvaginal ultrasound to look for fibroidsexternal icon or other anatomic abnormalities. If suspicion exists that the fibroids may be entering the endometrial cavity, a sonohystogram (SHG) or hysteroscopy (HSC) may be performed to further evaluate the uterine environment.
Not delaying parenthood. Fertility does not ultimately cease before menopause, but it starts declining after age 27 and drops at a somewhat greater rate after age 35.[60] Women whose biological mothers had unusual or abnormal issues related to conceiving may be at particular risk for some conditions, such as premature menopause, that can be mitigated by not delaying parenthood.
Not delaying parenthood. Fertility does not ultimately cease before menopause, but it starts declining after age 27 and drops at a somewhat greater rate after age 35.[60] Women whose biological mothers had unusual or abnormal issues related to conceiving may be at particular risk for some conditions, such as premature menopause, that can be mitigated by not delaying parenthood.
Damage to your fallopian tubes. These structures carry eggs from your ovaries, which produce eggs, to the uterus, where the baby develops. They can get damaged when scars form after pelvic infections, endometriosis, and pelvic surgery. That can prevent sperm from reaching an egg in the tube. The egg and sperm meet in the tube. This is where the egg is fertilized and then moves down to the uterus to implant..
Women who never have pregnancies have an increased risk of ovarian tumors, so it may be related to the underlying problem rather than the treatment. Since success rates are typically higher in the first few treatment cycles, re-evaluating medication use every few months and concentrating on the treatments that have the most success appear to be appropriate.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 8 Nov 2019), Cerner Multum™ (updated 6 Nov 2019), Wolters Kluwer™ (updated 4 Nov 2019) and others.
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