Tobacco smoking is harmful to the ovaries, and the degree of damage is dependent upon the amount and length of time a woman smokes or is exposed to a smoke-filled environment. Nicotine and other harmful chemicals in cigarettes interfere with the body’s ability to create estrogen, a hormone that regulates folliculogenesis and ovulation. Also, cigarette smoking interferes with folliculogenesis, embryo transport, endometrial receptivity, endometrial angiogenesis, uterine blood flow and the uterine myometrium.[8] Some damage is irreversible, but stopping smoking can prevent further damage.[9][10] Smokers are 60% more likely to be infertile than non-smokers.[11] Smoking reduces the chances of IVF producing a live birth by 34% and increases the risk of an IVF pregnancy miscarrying by 30%.[11] Also, female smokers have an earlier onset of menopause by approximately 1–4 years.[12]
Female infertility refers to infertility in women. It affects an estimated 48 million women,[2] with the highest prevalence of infertility affecting people in South Asia, Sub-Saharan Africa, North Africa/Middle East, and Central/Eastern Europe and Central Asia.[2] Infertility is caused by many sources, including nutrition, diseases, and other malformations of the uterus. Infertility affects women from around the world, and the cultural and social stigma surrounding it varies.
In vitro fertilization (IVF) is the most commonly used type of ART. This female infertility treatment has a pregnancy success rate similar to the rates of couples trying to get pregnant without assistance. If your doctor recommends in vitro fertilization as female infertility treatment, read more about this procedure so you fully understand the amazing process.